The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

WHIM syndrome is a rare congenital immunodeficiency disorder characterized by warts, hypogammaglobulinemia, infections, and myelokathexis (neutropenia because of impaired egress from the BM); most patients also have severe panleukopenia. Because WHIM syndrome is caused by mutations in the chemokine...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: McDermott, David H., Liu, Qian, Ulrick, Jean, Kwatemaa, Nana, Anaya-O'Brien, Sandra, Penzak, Scott R., Filho, Joao Oliveira, Priel, Debra A. Long, Kelly, Corin, Garofalo, Mary, Littel, Patricia, Marquesen, Martha M., Hilligoss, Diane, DeCastro, Rosamma, Fleisher, Thomas A., Kuhns, Douglas B., Malech, Harry L., Murphy, Philip M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2011
विषय:
Clinical Trials and Observations
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208300/
https://ncbi.nlm.nih.gov/pubmed/21890643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368084
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