CRRL269: a novel designer and renal-enhancing pGC-A peptide activator

The natriuretic peptides (NPs) B-type NP (BNP) and urodilatin (URO) exert renal protective properties via the particulate guanylyl cyclase A receptor (pGC-A). As a potential renal-enhancing strategy, we engineered a novel designer peptide that we call CRRL269. CRRL269 was investigated in human cell...

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Détails bibliographiques
Publié dans:Am J Physiol Regul Integr Comp Physiol
Auteurs principaux: Chen, Yang, Harty, Gail J., Huntley, Brenda K., Iyer, Seethalakshmi R., Heublein, Denise M., Harders, Gerald E., Meems, Laura, Pan, Shuchong, Sangaralingham, S. Jeson, Ichiki, Tomoko, Burnett, John C.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425618/
https://ncbi.nlm.nih.gov/pubmed/29187381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00286.2017
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