Differential expression of the pro-natriuretic peptide convertases corin and furin in experimental heart failure and atrial fibrosis

In heart failure (HF), the cardiac hormone natriuretic peptides (NPs) atrial (ANP), B-type (BNP), and C-type (CNP) play a key role to protect cardiac remodeling. The proprotein convertases corin and furin process their respective pro-NPs into active NPs. Here we define in a canine model of HF furin...

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Detalhes bibliográficos
Principais autores: Ichiki, Tomoko, Boerrigter, Guido, Huntley, Brenda K., Sangaralingham, S. Jeson, McKie, Paul M., Harty, Gail J., Harders, Gerald E., Burnett, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Cardiovascular and Renal Integration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543660/
https://ncbi.nlm.nih.gov/pubmed/23152112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00233.2012
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