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Pro-Atrial Natriuretic Peptide: A Novel Guanylyl Cyclase-A Receptor Activator Which Goes Beyond Atrial and B-type Natriuretic Peptides
OBJECTIVE: We sought to determine if the atrial natriuretic peptide (ANP) precursor proANP is biologically active compared to ANP and BNP. BACKGROUND: ProANP is produced in the atria and processed to ANP and activates the guanylyl cyclase receptor-A (GC-A) and its second messenger cGMP. ProANP is fo...
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| Udgivet i: | JACC Heart Fail |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568029/ https://ncbi.nlm.nih.gov/pubmed/26362447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchf.2015.03.015 |
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