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Pro-Atrial Natriuretic Peptide: A Novel Guanylyl Cyclase-A Receptor Activator Which Goes Beyond Atrial and B-type Natriuretic Peptides

OBJECTIVE: We sought to determine if the atrial natriuretic peptide (ANP) precursor proANP is biologically active compared to ANP and BNP. BACKGROUND: ProANP is produced in the atria and processed to ANP and activates the guanylyl cyclase receptor-A (GC-A) and its second messenger cGMP. ProANP is fo...

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Bibliografiska uppgifter
I publikationen:JACC Heart Fail
Huvudupphovsmän: Ichiki, Tomoko, Huntley, Brenda K., Sangaralingham, S. Jeson, Burnett, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568029/
https://ncbi.nlm.nih.gov/pubmed/26362447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchf.2015.03.015
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