Cardiac Fibrosis in End-Stage Human Heart Failure and the Cardiac Natriuretic Peptide Guanylyl Cyclase System: Regulation and Therapeutic Implications

Left ventricular assist device (LVAD) support has been used in the treatment of end-stage heart failure (HF), however use of anti-fibrotic co-therapies may improve prognosis. Natriuretic peptides (NPs) possess anti-fibrotic properties through their receptors, GC-A/GC-B/NPR-C. We sought to evaluate c...

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Detalhes bibliográficos
Main Authors: Ichiki, Tomoko, Schirger, John A, Huntley, Brenda K, Brozovich, Frank C, Maleszewski, Josef J, Sandberg, Sharon M, Sangaralingham, S Jeson, Park, Soon J, Burnett, John C
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157955/
https://ncbi.nlm.nih.gov/pubmed/25117468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.08.001
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