CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart

Natriuretic peptides (NPs) are cardioprotective through the activation of guanylyl cyclase (GC) receptors A and B. CD-NP, also known as cenderitide, is a novel engineered NP that was designed to uniquely serve as a first-in-class dual GC receptor agonist. Recognizing the aldosterone suppressing acti...

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Detalhes bibliográficos
Main Authors: Martin, Fernando L., Sangaralingham, S. Jeson, Huntley, Brenda K., McKie, Paul M., Ichiki, Tomoko, Chen, Horng H., Korinek, Josef, Harders, Gerald E., Burnett, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525541/
https://ncbi.nlm.nih.gov/pubmed/23272242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052422
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