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The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge

In rodents, the preovulatory LH surge is temporally gated, but the timing cue is unknown. Estrogen primes neurons in the anteroventral periventricular nucleus (AVPV) to secrete kisspeptin, which potently activates GnRH neurons to release GnRH, eliciting a surge of LH to induce ovulation. Deletion of...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Tonsfeldt, Karen J, Schoeller, Erica L, Brusman, Liza E, Cui, Laura J, Lee, Jinkwon, Mellon, Pamela L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425515/
https://ncbi.nlm.nih.gov/pubmed/30906911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2018-00228
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