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The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge

In rodents, the preovulatory LH surge is temporally gated, but the timing cue is unknown. Estrogen primes neurons in the anteroventral periventricular nucleus (AVPV) to secrete kisspeptin, which potently activates GnRH neurons to release GnRH, eliciting a surge of LH to induce ovulation. Deletion of...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Tonsfeldt, Karen J, Schoeller, Erica L, Brusman, Liza E, Cui, Laura J, Lee, Jinkwon, Mellon, Pamela L
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425515/
https://ncbi.nlm.nih.gov/pubmed/30906911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2018-00228
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