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Hypersensitive interferon responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus

Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which 70% of patients experience disfiguring skin inflammation (grouped under the rubric of cutaneous lupus erythematosus, CLE). There are limited treatment options for SLE and no FDA-approved therapies for CLE. Studies have revea...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Tsoi, Lam C., Hile, Grace A., Berthier, Celine C., Sarkar, Mrinal K., Reed, Tamra J., Liu, Jianhua, Uppala, Ranjitha, Patrick, Matthew, Raja, Kalpana, Xing, Xianying, Xing, Enze, He, Kevin, Gudjonsson, Johann E., Kahlenberg, J. Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424612/
https://ncbi.nlm.nih.gov/pubmed/30745462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800650
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