A Novel Crosslinking Protocol Stabilizes Amyloid β Oligomers Capable of Inducing Alzheimer’s-Associated Pathologies

Amyloid β oligomers (AβOs) accumulate early in Alzheimer’s disease (AD) and experimentally cause memory dysfunction and the major pathologies associated with AD, e.g., tau abnormalities, synapse loss, oxidative damage, and cognitive dysfunction. In order to develop the most effective AβO-targeting d...

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Bibliographic Details
Published in:J Neurochem
Main Authors: Cline, Erika N., Das, Arighno, Bicca, Maíra Assunção, Mohammad, Saad N., Schachner, Luis F., Kamel, Josette M., DiNunno, Nadia, Weng, Anthea, Paschall, Jacob D., Bu, Riana Lo, Khan, Faraz M., Rollins, Madeline G., Ives, Ashley N., Shekhawat, Gajendra, Nunes-Tavares, Nilson, de Mello, Fernando G., Compton, Philip D., Kelleher, Neil L., Klein, William L.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424489/
https://ncbi.nlm.nih.gov/pubmed/30565253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14647
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