A Novel Crosslinking Protocol Stabilizes Amyloid β Oligomers Capable of Inducing Alzheimer’s-Associated Pathologies

Amyloid β oligomers (AβOs) accumulate early in Alzheimer’s disease (AD) and experimentally cause memory dysfunction and the major pathologies associated with AD, e.g., tau abnormalities, synapse loss, oxidative damage, and cognitive dysfunction. In order to develop the most effective AβO-targeting d...

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Veröffentlicht in:J Neurochem
Hauptverfasser: Cline, Erika N., Das, Arighno, Bicca, Maíra Assunção, Mohammad, Saad N., Schachner, Luis F., Kamel, Josette M., DiNunno, Nadia, Weng, Anthea, Paschall, Jacob D., Bu, Riana Lo, Khan, Faraz M., Rollins, Madeline G., Ives, Ashley N., Shekhawat, Gajendra, Nunes-Tavares, Nilson, de Mello, Fernando G., Compton, Philip D., Kelleher, Neil L., Klein, William L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424489/
https://ncbi.nlm.nih.gov/pubmed/30565253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14647
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