A Peptidylic Inhibitor for Neutralizing (r)(GGGGCC)(exp)-Associated Neurodegeneration in C9ALS-FTD

One drug, two diseases is a rare and economical therapeutic strategy that is highly desirable in the pharmaceutical industry. We previously reported a 21-amino acid peptide named beta-structured inhibitor for neurodegenerative diseases (BIND) that can effectively inhibit expanded CAG trinucleotide t...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Zhang, Qian, An, Ying, Chen, Zhefan Stephen, Koon, Alex Chun, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424097/
https://ncbi.nlm.nih.gov/pubmed/30889483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.015
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