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Stereoselective and Regioselective Intramolecular Friedel-Crafts Reaction of Aziridinium Ions for Synthesis of 4-Substituted Tetrahydroisoquinolines
Optically active 4-substituted tetrahydroisoquinolines were synthesized via intramolecular Friedel-Crafts (FC) reactions of aziridinium ions in a highly regioselective and stereoselective manner. Control experiments suggest the formation and ring opening of aziridinium ions as the key intermediates...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423956/ https://ncbi.nlm.nih.gov/pubmed/24245533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4013537 |
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