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Biocatalytic Friedel–Crafts Acylation and Fries Reaction

The Friedel–Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo‐ and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel–Crafts C‐acylation of...

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Библиографические подробности
Опубликовано в: :Angew Chem Int Ed Engl
Главные авторы: Schmidt, Nina G., Pavkov‐Keller, Tea, Richter, Nina, Wiltschi, Birgit, Gruber, Karl, Kroutil, Wolfgang
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488191/
https://ncbi.nlm.nih.gov/pubmed/28544673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703270
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