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Directed evolution studies of a thermophilic Type II-C Cas9
Though making up nearly half of the known CRISPR–Cas9 family of enzymes, the Type II-C CRISPR–Cas9 has been underexplored for their molecular mechanisms and potential in safe gene editing applications. In comparison with the more popular Type II-A CRISPR–Cas9, the Type II-C enzymes are generally sma...
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| Udgivet i: | Methods Enzymol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423443/ https://ncbi.nlm.nih.gov/pubmed/30691646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.10.029 |
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