[Ru(bpy)(2)(NO)SO(3)](PF(6)), a Nitric Oxide Donating Ruthenium Complex, Reduces Gout Arthritis in Mice

Monosodium urate crystals (MSU) deposition induces articular inflammation known as gout. This disease is characterized by intense articular inflammation and pain by mechanisms involving the activation of the transcription factor NFκB and inflammasome resulting in the production of cytokines and oxid...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Rossaneis, Ana C., Longhi-Balbinot, Daniela T., Bertozzi, Mariana M., Fattori, Victor, Segato-Vendrameto, Carina Z., Badaro-Garcia, Stephanie, Zaninelli, Tiago H., Staurengo-Ferrari, Larissa, Borghi, Sergio M., Carvalho, Thacyana T., Bussmann, Allan J. C., Gouveia, Florêncio S., Lopes, Luiz G. F., Casagrande, Rubia, Verri, Waldiceu A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423075/
https://ncbi.nlm.nih.gov/pubmed/30914954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00229
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