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Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation
Chronic infections of the fallopian tubes with Chlamydia trachomatis (Ctr) cause scarring and can lead to infertility. Here we use human fallopian tube organoids and genital Ctr serovars D, K and E for long-term in vitro analysis. The epithelial monolayer responds with active expulsion of the bacter...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423033/ https://ncbi.nlm.nih.gov/pubmed/30886143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09144-7 |
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