The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids

The epithelial lining of the fallopian tube is of critical importance for human reproduction and has been implicated as a site of origin of high-grade serous ovarian cancer. Here we report on the establishment of long-term, stable 3D organoid cultures from human fallopian tubes, indicative of the pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kessler, Mirjana, Hoffmann, Karen, Brinkmann, Volker, Thieck, Oliver, Jackisch, Susan, Toelle, Benjamin, Berger, Hilmar, Mollenkopf, Hans-Joachim, Mangler, Mandy, Sehouli, Jalid, Fotopoulou, Christina, Meyer, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686873/
https://ncbi.nlm.nih.gov/pubmed/26643275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9989
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