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Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation

The absence of Ataxia-Telangiectasia mutated protein kinase (ATM) is associated with neurological, metabolic and cardiovascular defects. The protein has been associated with mitochondria and its absence results in mitochondrial dysfunction. Furthermore, it can be activated in the cytosol by mitochon...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Blignaut, Marguerite, Loos, Ben, Botchway, Stanley W., Parker, Anthony W., Huisamen, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423017/
https://ncbi.nlm.nih.gov/pubmed/30886180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41108-1
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