Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity

AIMS: Doxorubicin (Dox) is a potent anticancer agent that is widely used in the treatment of a variety of cancers, but its usage is limited by cumulative dose-dependent cardiotoxicity mainly due to oxidative damage. Ataxia telangiectasia mutated (ATM) kinase is thought to play a role in mediating th...

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Detaylı Bibliyografya
Yayımlandı:Cardiovasc Res
Asıl Yazarlar: Zhan, Hong, Aizawa, Kenichi, Sun, Junqing, Tomida, Shota, Otsu, Kinya, Conway, Simon J., Mckinnon, Peter J., Manabe, Ichiro, Komuro, Issei, Miyagawa, Kiyoshi, Nagai, Ryozo, Suzuki, Toru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798048/
https://ncbi.nlm.nih.gov/pubmed/26862121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw032
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