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Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation

The absence of Ataxia-Telangiectasia mutated protein kinase (ATM) is associated with neurological, metabolic and cardiovascular defects. The protein has been associated with mitochondria and its absence results in mitochondrial dysfunction. Furthermore, it can be activated in the cytosol by mitochon...

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Pubblicato in:Sci Rep
Autori principali: Blignaut, Marguerite, Loos, Ben, Botchway, Stanley W., Parker, Anthony W., Huisamen, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423017/
https://ncbi.nlm.nih.gov/pubmed/30886180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41108-1
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