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Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be precipitated by exposure to chronic stress. For decades, the monoaminergic deficit hypothesis of depression pro...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Fogaça, Manoela V., Duman, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422907/
https://ncbi.nlm.nih.gov/pubmed/30914923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00087
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