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Synaptic Dysfunction in Depression: Potential Therapeutic Targets

Basic and clinical studies demonstrate that depression is associated with reduced size of brain regions that regulate mood and cognition, including the prefrontal cortex and the hippocampus, and decreased neuronal synapses in these areas. Antidepressants can block or reverse these neuronal deficits,...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Duman, Ronald S., Aghajanian, George K.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424898/
https://ncbi.nlm.nih.gov/pubmed/23042884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222939
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