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Prefrontal Cortex GABAergic Deficits and Circuit Dysfunction in the Pathophysiology and Treatment of Chronic Stress and Depression

Psychiatric diseases, notably major depression, are associated with imbalance of excitatory and inhibitory neurotransmission within the prefrontal cortex (PFC) and related limbic brain circuitry. In many cases these illnesses are precipitated or exacerbated by chronic stress, which also alters excit...

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Detalhes bibliográficos
Publicado no:Curr Opin Behav Sci
Main Authors: Ghosal, Sriparna, Hare, Brendan, Duman, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086803/
https://ncbi.nlm.nih.gov/pubmed/27812532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobeha.2016.09.012
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