Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas

BACKGROUND: Mutations in telomerase reverse transcriptase promoter (TERTp) and isocitrate dehydrogenase 1 and 2 (IDH) offer objective markers to assist in classifying diffuse gliomas into genetic subgroups. However, traditional mutation detection techniques lack sensitivity or have long turnaround t...

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Vydáno v:Neuro Oncol
Hlavní autoři: Diplas, Bill H, Liu, Heng, Yang, Rui, Hansen, Landon J, Zachem, Alexis L, Zhao, Fangping, Bigner, Darell D, McLendon, Roger E, Jiao, Yuchen, He, Yiping, Waitkus, Matthew S, Yan, Hai
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422442/
https://ncbi.nlm.nih.gov/pubmed/30346624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy167
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