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Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals

G protein–coupled receptors (GPCRs) play an important role in physiology and disease and represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands unknown, were considered a source of drug targets and consequently attract great interest to identify their endogenous cogn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Biol
Hauptverfasser: Tang, Huihao, Shu, Chuanjun, Chen, Haidi, Zhang, Xiaojing, Zang, Zhuqing, Deng, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422423/
https://ncbi.nlm.nih.gov/pubmed/30840614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000175
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