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Molecular basis for agonist selectivity and activation of the orphan BRS-3-receptor

Bombesin receptor subtype-3(BRS-3), a G protein-coupled orphan receptor, shares 51% identity with the mammalian bombesin(Bn) receptor for gastrin-releasing peptide(GRPR). There is increasing interest in BRS-3 because it is important in energy metabolism, glucose control,motility and tumor-growth. BR...

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Bibliografiske detaljer
Main Authors: Gonzalez, Nieves, Hocart, Simon J., Portal-Nuñez, Sergio, Mantey, Samuel A., Nakagawa, Tomoo, Zudaire, Enrique, Coy, David H., Jensen, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593135/
https://ncbi.nlm.nih.gov/pubmed/18006692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.132332
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