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Orphan GPCR research

Orphan G protein-coupled receptors (GPCRs) are receptors lacking endogenous ligands. Found by molecular biological analyses, they became the roots of reverse pharmacology, in which receptors are attempted to be matched to potential transmitters. Later, when high-throughput screening technology was a...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chung, S, Funakoshi, T, Civelli, O
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268047/
https://ncbi.nlm.nih.gov/pubmed/18071299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707606
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