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Orphan GPCR research

Orphan G protein-coupled receptors (GPCRs) are receptors lacking endogenous ligands. Found by molecular biological analyses, they became the roots of reverse pharmacology, in which receptors are attempted to be matched to potential transmitters. Later, when high-throughput screening technology was a...

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Detalhes bibliográficos
Main Authors: Chung, S, Funakoshi, T, Civelli, O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268047/
https://ncbi.nlm.nih.gov/pubmed/18071299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707606
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