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Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor
Lactisole, an inhibitor of the human sweet taste receptor, has a 2-phenoxypropionic acid skeleton and has been shown to interact with the transmembrane domain of the T1R3 subunit (T1R3-TMD) of the receptor. Another inhibitor, 2,4-DP, which shares the same molecular skeleton as lactisole, was confirm...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422327/ https://ncbi.nlm.nih.gov/pubmed/30883570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213552 |
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