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Asymmetric Synthesis of Photophore-Containing Lactisole Derivatives to Elucidate Sweet Taste Receptors

Lactisole, which has a 2-phenoxy propionic acid skeleton, is well-known as an inhibitor of sweet taste receptors. We recently revealed some of the structure–activity relationships of the aromatic ring and chiral center of lactisole. Photoaffinity labeling is one of the common chemical biology method...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Nakagita, Tomoya, Ishida, Akiko, Tachrim, Zetryana Puteri, Wang, Lei, Misaka, Takumi, Hashimoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355818/
https://ncbi.nlm.nih.gov/pubmed/32560345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122790
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