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Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design
P-Glycoprotein (P-gp), a transmembrane, ATP-dependent drug efflux transporter, has attracted considerable interest both with respect to its role in tumour cell multi-drug resistance and in absorption-distribution and elimination of drugs. Although known since more than 30 years, the understanding of...
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| Publicado no: | Mol Inform |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422301/ https://ncbi.nlm.nih.gov/pubmed/27463054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201000017 |
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