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Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design

P-Glycoprotein (P-gp), a transmembrane, ATP-dependent drug efflux transporter, has attracted considerable interest both with respect to its role in tumour cell multi-drug resistance and in absorption-distribution and elimination of drugs. Although known since more than 30 years, the understanding of...

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Podrobná bibliografie
Vydáno v:Mol Inform
Hlavní autoři: Klepsch, Freya, Ecker, Gerhard F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422301/
https://ncbi.nlm.nih.gov/pubmed/27463054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201000017
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