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A high-throughput chemical–genetics screen in murine adipocytes identifies insulin-regulatory pathways

Pathways linking activation of the insulin receptor to downstream targets of insulin have traditionally been studied using a candidate gene approach. To elucidate additional pathways regulating insulin activity, we performed a forward chemical–genetics screen based on translocation of a glucose tran...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Brewer, Paul Duffield, Romenskaia, Irina, Mastick, Cynthia Corley
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422095/
https://ncbi.nlm.nih.gov/pubmed/30591588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006986
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