Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia

Congenital myasthenic syndromes (CMS) result from reduced cholinergic transmission at neuromuscular junctions (NMJs). While the etiology of CMS varies, the disease is characterized by muscle weakness. To date, it remains unknown if CMS causes long-term and irreversible changes to skeletal muscles. I...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurochem Int
Autori principali: Magalhães-Gomes, Matheus P.S., Motta-Santos, Daisy, Schetino, Luana P.L., Andrade, Jéssica N., Bastos, Cristiane P., Guimarães, Diogo A.S., Vaughan, Sydney K., Martinelli, Patrícia M., Guatimosim, Silvia, Pereira, Grace S., Coimbra, Candido C., Prado, Vânia F., Prado, Marco A.M., Valdez, Gregorio, Guatimosim, Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421860/
https://ncbi.nlm.nih.gov/pubmed/30003945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2018.07.002
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi