Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia

Congenital myasthenic syndromes (CMS) result from reduced cholinergic transmission at neuromuscular junctions (NMJs). While the etiology of CMS varies, the disease is characterized by muscle weakness. To date, it remains unknown if CMS causes long-term and irreversible changes to skeletal muscles. I...

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Publicado no:Neurochem Int
Main Authors: Magalhães-Gomes, Matheus P.S., Motta-Santos, Daisy, Schetino, Luana P.L., Andrade, Jéssica N., Bastos, Cristiane P., Guimarães, Diogo A.S., Vaughan, Sydney K., Martinelli, Patrícia M., Guatimosim, Silvia, Pereira, Grace S., Coimbra, Candido C., Prado, Vânia F., Prado, Marco A.M., Valdez, Gregorio, Guatimosim, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421860/
https://ncbi.nlm.nih.gov/pubmed/30003945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2018.07.002
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