Differential Requirement of Cd8 Enhancers E8(I) and E8(VI) in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes

CD8 expression in T lymphocytes is tightly regulated by the activity of at least six Cd8 enhancers (E8(I)-E8(VI)), however their complex developmental stage-, subset-, and lineage-specific interplays are incompletely understood. Here we analyzed ATAC-seq data on the Immunological Genome Project data...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Gülich, Alexandra Franziska, Preglej, Teresa, Hamminger, Patricia, Alteneder, Marlis, Tizian, Caroline, Orola, Maria Jonah, Muroi, Sawako, Taniuchi, Ichiro, Ellmeier, Wilfried, Sakaguchi, Shinya
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421288/
https://ncbi.nlm.nih.gov/pubmed/30915074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00409
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