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Immunogenicity characterization of genetically fused or chemically conjugated heat-stable toxin toxoids of enterotoxigenic Escherichia coli in mice and pigs

Enterotoxigenic Escherichia coli (ETEC) producing type Ib heat-stable toxin (STa) are a main cause of children's diarrhea and travelers’ diarrhea, thus STa needs to be targeted in ETEC vaccine development. However, because this 19-amino acid STa is poorly immunogenic, attempts to genetically fu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:FEMS Microbiol Lett
Hauptverfasser: Seo, Hyesuk, Lu, Ti, Nandre, Rahul M, Duan, Qiangde, Zhang, Weiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420877/
https://ncbi.nlm.nih.gov/pubmed/30772899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsle/fnz037
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