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Neutralizing Anti-Heat-Stable Toxin (STa) Antibodies Derived from Enterotoxigenic Escherichia coli Toxoid Fusions with STa Proteins Containing N12S, L9A/N12S, or N12S/A14T Mutations Show Little Cross-Reactivity with Guanylin or Uroguanylin

Heat-stable toxin (STa)-producing enterotoxigenic Escherichia coli (ETEC) strains are a top cause of moderate-to-severe diarrhea in children from developing countries and a common cause of travelers' diarrhea. Recent progress in using STa toxoids and toxoid fusions to induce neutralizing anti-S...

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Bibliografiska uppgifter
I publikationen:Appl Environ Microbiol
Huvudupphovsmän: Duan, Qiangde, Huang, Jiachen, Xiao, Nan, Seo, Hyesuk, Zhang, Weiping
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752861/
https://ncbi.nlm.nih.gov/pubmed/29079628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01737-17
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