Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury

BACKGROUND: Studies have shown that transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) protects against brain damage. However, the low survival number of transplanted BMSCs remains a pertinent challenge and can be attributed to the unfavorable microenvironment of the injured brain...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Hu, Jiangnan, Chen, Lefu, Huang, Xujun, Wu, Ke, Ding, Saidan, Wang, Weikan, Wang, Brian, Smith, Charity, Ren, Changhong, Ni, Haoqi, ZhuGe, Qichuan, Yang, Jianjing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420775/
https://ncbi.nlm.nih.gov/pubmed/30876457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1210-4
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