The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes

BACKGROUND: Human cutaneous leishmaniasis is caused by distinct species, including Leishmania amazonensis. Treatment of cutaneous leishmaniasis is far from satisfactory due to increases in drug resistance and relapses, and toxicity of compounds to the host. As a consequence for this situation, the d...

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Bibliographic Details
Main Authors: Marinho, Fernanda A., Gonçalves, Keyla C. S., Oliveira, Simone S. C., Gonçalves, Diego S., Matteoli, Filipe P., Seabra, Sergio H., Oliveira, Ana Carolina S., Bellio, Maria, Oliveira, Selma S., Souto-Padrón, Thaïs, d'Avila-Levy, Claudia M., Santos, André L. S., Branquinha, Marta H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909198/
https://ncbi.nlm.nih.gov/pubmed/24498160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087659
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