A Pharmacological Analysis of the Neuroprotective Efficacy of the Brain- and Cell-Permeable Calpain Inhibitor MDL-28170 in the Mouse Controlled Cortical Impact Traumatic Brain Injury Model

The cytoskeletal and neuronal protective effects of early treatment with the blood–brain barrier- and cell-permeable calpain inhibitor MDL-28170 was examined in the controlled cortical impact (CCI) traumatic brain injury (TBI) model in male CF-1 mice. This was preceded by a dose-response and pharmac...

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Hlavní autoři: Thompson, Stephanie N., Carrico, Kimberly M., Mustafa, Ayman G., Bains, Mona, Hall, Edward D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996835/
https://ncbi.nlm.nih.gov/pubmed/20874056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2010.1474
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