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Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge. Here, we develop a genome editing strategy using...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Hwang, Byungjin, Lee, Wookjae, Yum, Soo-Young, Jeon, Yujin, Cho, Namjin, Jang, Goo, Bang, Duhee
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420643/
https://ncbi.nlm.nih.gov/pubmed/30874552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09203-z
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