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Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge. Here, we develop a genome editing strategy using...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Hwang, Byungjin, Lee, Wookjae, Yum, Soo-Young, Jeon, Yujin, Cho, Namjin, Jang, Goo, Bang, Duhee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420643/
https://ncbi.nlm.nih.gov/pubmed/30874552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09203-z
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