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Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge. Here, we develop a genome editing strategy using...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Hwang, Byungjin, Lee, Wookjae, Yum, Soo-Young, Jeon, Yujin, Cho, Namjin, Jang, Goo, Bang, Duhee
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420643/
https://ncbi.nlm.nih.gov/pubmed/30874552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09203-z
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