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Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive

Hypothermia induced at the onset of ischemia is a potent experimental cardioprotective strategy for myocardial infarction. The aim of our study was to determine whether the beneficial effects of hypothermia may be due to decreasing mitochondria-mediated mechanisms of damage that contribute to the pa...

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Publicat a:Basic Res Cardiol
Autors principals: Kohlhauer, M., Pell, V. R., Burger, N., Spiroski, A. M., Gruszczyk, A., Mulvey, J. F., Mottahedin, Amin, Costa, A. S. H., Frezza, C., Ghaleh, B., Murphy, M. P., Tissier, R., Krieg, T.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420484/
https://ncbi.nlm.nih.gov/pubmed/30877396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-019-0727-0
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