Mechanism of succinate efflux upon reperfusion of the ischaemic heart

AIMS : Succinate accumulates several-fold in the ischaemic heart and is then rapidly oxidized upon reperfusion, contributing to reactive oxygen species production by mitochondria. In addition, a significant amount of the accumulated succinate is released from the heart into the circulation at reperf...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Prag, Hiran A, Gruszczyk, Anja V, Huang, Margaret M, Beach, Timothy E, Young, Timothy, Tronci, Laura, Nikitopoulou, Efterpi, Mulvey, John F, Ascione, Raimondo, Hadjihambi, Anna, Shattock, Michael J, Pellerin, Luc, Saeb-Parsy, Kourosh, Frezza, Christian, James, Andrew M, Krieg, Thomas, Murphy, Michael P, Aksentijević, Dunja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983001/
https://ncbi.nlm.nih.gov/pubmed/32766828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa148
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