The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic

Esophageal adenocarcinoma (EAC) is a poor prognosis cancer type with rapidly rising incidence. Our understanding of genetic events that drive EAC development is limited, and there are few molecular biomarkers for prognostication or therapeutics. Using a cohort of 551 genomically characterized EACs w...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Frankell, Alexander M, Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420087/
https://ncbi.nlm.nih.gov/pubmed/30718927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0331-5
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