Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

Esophageal adenocarcinoma (EAC) develops in an inflammatory microenvironment with reduced microbial diversity, but mechanisms for these influences remain poorly characterized. We hypothesized that mutations targeting the Toll-like receptor (TLR) pathway could disrupt innate immune signaling and prom...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Fels Elliott, Daffolyn Rachael, Perner, Juliane, Li, Xiaodun, Symmons, Martyn F., Verstak, Brett, Eldridge, Matthew, Bower, Lawrence, O’Donovan, Maria, Gay, Nick J., Fitzgerald, Rebecca C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460900/
https://ncbi.nlm.nih.gov/pubmed/28531216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006808
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