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Bacterial sensors define intracellular free energies for correct enzyme metalation

There is a challenge for metalloenzymes to acquire their correct metals because some inorganic elements form more stable complexes with proteins than do others. These preferences can be overcome provided some metals are more available than others. However, while the total amount of cellular metal ca...

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Pubblicato in:Nat Chem Biol
Autori principali: Osman, Deenah, Martini, Maria Alessandra, Foster, Andrew W., Chen, Junjun, Scott, Andrew J. P., Morton, Richard J., Steed, Jonathan W., Lurie-Luke, Elena, Huggins, Thomas G., Lawrence, Andrew D., Deery, Evelyne, Warren, Martin J., Chivers, Peter T., Robinson, Nigel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420079/
https://ncbi.nlm.nih.gov/pubmed/30692683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0211-4
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