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Fine control of metal concentrations is necessary for cells to discern zinc from cobalt
Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific metals, but metal binding is not specific in vitro. Here we show that tight regulation of buffered intracellular metal concentrations is a prerequisite for metal specificity of Zur, ZntR, RcnR and F...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709419/ https://ncbi.nlm.nih.gov/pubmed/29192165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02085-z |
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