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Human genes escaping X-inactivation revealed by single cell expression data

BACKGROUND: In mammals, sex chromosomes pose an inherent imbalance of gene expression between sexes. In each female somatic cell, random inactivation of one of the X-chromosomes restores this balance. While most genes from the inactivated X-chromosome are silenced, 15–25% are known to escape X-inact...

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Pubblicato in:BMC Genomics
Autori principali: Wainer Katsir, Kerem, Linial, Michal
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419355/
https://ncbi.nlm.nih.gov/pubmed/30871455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5507-6
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